Abstract：Studies of PEGfunctionlized N-heterocyclic carbenephosphine palladium catalyst［Cat(n=15)］ for coupling 4-bromotoluene（1） with phenylboronic acid（2） in aqueousphase have been carried out. Effects of PEG kinds and amount, Cat dosage on Suzuki coupling were investigateed. The results showed that 50%PEG400 as co-solvent, the catalytic activities of Cat was similar with in 1,4-dioxane, and the conversion of 1 was nearly 100% at 110 ℃ for 3 h at loading of 0.1 mol%, and was 57% at 0.01 mol% at 110 ℃ for 21 h(TON 5 700). It was found that the Cat can be recycled and reused once at loading of 0.1 mol%.
贾莉. 聚乙二醇功能化的N-杂环卡宾-膦Pd催化剂在水相中的Suzuki反应研究[J]. 合成化学, 2015, 23(12): 1158-1161.
JIA Li. Study on PEGfunctionlized N-heterocyclic Carbene-phosphine Palladium Catalyst for Suzuki CouplingReaction in Aqueous Phase. Chinese Journal of Synthetic Chemistry, 2015, 23(12): 1158-1161.
2015, Vol. 23 
