Synthesis and Antibacterial Activities of Novel Vanillin Benzimidazole Schiff Bases
DENG Ping1,2, WU Min1,2
1. College of Life Science & Technology, Yulin Normal University, Yulin 537000, China; 2. Cultivation Base for Key Laboratory of Conservation and Utilization of Rare and Economic Species at Southeast, Yulin 537000, China
Abstract：Three novel vanillin benzimidazole Schiff bases(5a~5c) were synthesized, using o-phenylenediamine and vanillin as raw materials. The structures were characterized by 1H NMR and IR. The antibacterial activities of 5a~5c against Fusarium oxysporium(F.oxy), Alternaria solani(A.sol), Fusarium graminearum(F.gra), Cercospora sorghi(C.sor) and Fusaurium oxysporiumf. sp. vasinfectum(F.oxy) were investigated by mycelial growth rate method. The results indicated that 5c exhibited better antimicrobial activities against F.gra, F.ox and C.sor than Carbendazim with EC50 of 19.76 mg·L-1， 24.94 mg·L-1 and 29.15 mg·L-1.
邓平， 吴敏. 新型香草醛缩苯并咪唑Schiff碱的合成及其抑菌活性[J]. 合成化学, 2016, 24(2): 148-151.
DENG Ping, WU Min. Synthesis and Antibacterial Activities of Novel Vanillin Benzimidazole Schiff Bases. Chinese Journal of Synthetic Chemistry, 2016, 24(2): 148-151.