Preparation and Characterization of Poly(lactide-co-glycolide-co-caprolactone)s Random Terpolymer
YANG Huan1,2, HUANG Dong-ling1,2, CHEN Dong-liang1,XIONG Cheng-dong1, ZHANG Qi3, PANG Xiu-bing4, XIONG Zuo-chun1
1. Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China; 2. University of Chinese Academy of Sciences, Beijing 100049, China; 3. Clinical Research Institute, Zhejiang Province People’s Hospital, Hangzhou 310014, China; 4. Engineering Research Center of Biodegradation Medical Meterials of Zhejiang Province, Dongyang 322118, Chian
Abstract:Random terpolymers(P) of L-lactide, glycolide and caprolactone had been prepared by bulk ring-opening copolymerization initiated by stannous octoate under high vacuum. The sttucture and properties had been investigated by 1H NMR, IR, DSC and viscosimetry. The results indicated that the glass transition temperature of P can be controlled by adjusting the monomer ration. The submicron fiber membrane of P can be obtained easily through electrospinning.