Abstract：3,5-Dimethyl-N-［(1S,4S)-1,7,7-trimethylbicyclo［2.2.1］heptan-2-ylidene］aniline(1) was prepared by microwave-assisted condensation of 3,5-dimethylaniline with 2-camphonone. 1-(3,5-Dimethylphenyl)-1-［(1S,4S)-1,7,7-trimethylbicyclo［2.2.1］heptan-2-yl］hydrazine in total yield of 70.4% was synthesized by reduction of 1 by NaBH4 followed by amination with hydroxylamine O-sulfonic acid. The structures were confirmed by 1H NMR and ESI-MS.
王凯， 陈强， 张秀芹， 岳邦毅. 1-(3,5-二甲基苯基)-1-［(1S,4S)-1,7,7-三甲基双环-［2.2.1］庚烷-2-基］肼的合成工艺改进[J]. 合成化学, 2016, 24(3): 253-255.
WANG Kai, CHEN Qiang, ZHANG Xiu-qin, YUE Bang-yi. Process Improvement on the Synthesis of 1-(3,5-Dimethylphenyl)-1-［(1S,4S)-1,7,7-trimethyl-bicyclo［2.2.1］heptan-2-yl］hydrazine. Chinese Journal of Synthetic Chemistry, 2016, 24(3): 253-255.
2016, Vol. 24 
