Abstract：Two novel oxovanadium(IV) complexes， VO(dtbsal-met)(phen)（1） and VO(naph-met)(phen)（2）, were synthesized by aldimine condensation reaction reaction, using L-methionine(meth), 1,10-phenanthroline(phen)， 3,5-di-tert-butyl salicylaldehyde(dtbsali)［or 2-hydroxy-1-naphthaldehyde（hnaph）］ as materials. The structures were characterized by IR, HR-ESI-MS， molar conductance and single-crystal X-ray. 1（CCDC：1 429 158） and 2（CCDC：1 429 159）belongs to monoclinic crystal system and triclinic system， respectively． The in vitro anticancer activities of 1 and 2 against A549 and HeGp2 were tested by MTT method. The results showed that 1 and 2 exhibited certain antitumor activities.
曹亚萍, 易岑兰, 刘洪梅, 李海霞, 左建丽, 袁泽利. 新型氧钒(IV)席夫碱配合物［VO(dtbsal-met)(phen)和VO(naph-met)(phen)］的合成及其抗肿瘤活性[J]. 合成化学, 2015, 23(12): 1124-1129.
CAO Ya-ping, YI Cen-lan, LIU Hong-mei,LI Hai-xia, ZUO Jian-li, YUAN Ze-li. Synthesis and Anticancer Activities of Novel Oxovanadium(IV) Complexes［VO(dtbsal-met)(phen) and VO(naph-met)(phen)］. Chinese Journal of Synthetic Chemistry, 2015, 23(12): 1124-1129.
2015, Vol. 23 
