Synthesis of Photo-sensitive Supported-Proline and Their Application in Asymmetric Aldol Reaction in Water
LI Guang-feng， HUANG Yan-gen
National Engineering Research Center for Dyeing and Finishing of Textiles, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, China
Abstract：RAFT polymerization was successfully applied to the synthesis of the photo-sensitive supported catalysts(P) containing L-proline, coumarin and polyethylene glycol. The structures were characterized by 1H NMR and elemental analysis. UV spectra showed that the structures of P changed before and after UV irradiation. The catalytic performance indicated that Aldol reaction between cyclohexanone and 4-nitrobenzaldehyde in water can be achieved under the catalysis of P both before and after UV irradiation. The yields were 65%~76%, dr>93/7, and ee>95%.
李光锋， 黄焰根. 光响应负载型脯氨酸的合成及其在水相中催化不对称羟醛缩合反应的应用[J]. 合成化学, 2016, 24(1): 39-42.
LI Guang-feng， HUANG Yan-gen. Synthesis of Photo-sensitive Supported-Proline and Their Application in Asymmetric Aldol Reaction in Water. Chinese Journal of Synthetic Chemistry, 2016, 24(1): 39-42.
2016, Vol. 24 
