|
|
|
| Research of Synthetic Process of Sodium 3-Chloro-2-hydroxy Propanesulfate |
| GE Li-juan1,2, LIU Bai-ling2, ZHANG Yong3,LI Chen-ying1,2, LUO Rong2, CHEN Hua-lin2 |
| 1. University of Chinese Academy of Sciences， Beijing 100049， China； 2. Chengdu Organic Chemicals Co., Ltd., Chinese Academy of Sciences， Chengdu 610041， China；v3. Sichuan Flower’s Song Fine Chemical Co., Ltd., Zigong 643113， China |
|
|
|
|
Abstract A important intermediate of sulfonate amphoteric surfactant, sodium 3-chloro-2-hydroxy propanesulfate（2）， was synthesized by acidcatalyted ringopening reaction, using epichlorohydrin(1) and NaHSO3 as material, Na2SO3 as initiator， EDTA2 Na as complexing synergist． The structure was confirmed by 1H NMR, IR and ESI-MS. The yield of 2 was 81.55% under the optimum reaction conditions［1 0.55 mol, n(NaHSO3）: n（Na2SO3）: n（EDTA2Na）: n（H2O)=1.00 : 0.04 : 0.01 : 9.50， dropping time of 1 was 15 min, rotating speed is varied from 100 rpm to 300 rpm, at 70 ℃ for 1.25 h］.
|
|
Received: 29 January 2015
|
|
|
|
|
|
|
2015, Vol. 23 
