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A New Method of N-Debenzylation of Nitrogen Aromatic Heterocyclic Compounds |
ZHU Wen-tong, GAN Hai-feng, CHEN Zheng-bang, GUO Kai |
College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, China |
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Abstract The reaction of N-substituted benzylcarbazoles(or N-substituted benzylindoles) with potassium tert-butoxide resulted in debenzylation to carbazole(or indole) in oxygen. The yields were 68%~94%(or 75%~89%). The structures were confirmed by 1H NMR and 13C NMR.
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Received: 27 November 2014
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