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| Study on PEGfunctionlized N-heterocyclic Carbene-phosphine Palladium Catalyst for Suzuki CouplingReaction in Aqueous Phase |
| JIA Li |
| Key Laboratory of Polymer Materials of Fujian Province, Fujian Normal University, Fuzhou 350007, China |
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Abstract Studies of PEGfunctionlized N-heterocyclic carbenephosphine palladium catalyst［Cat(n=15)］ for coupling 4-bromotoluene（1） with phenylboronic acid（2） in aqueousphase have been carried out. Effects of PEG kinds and amount, Cat dosage on Suzuki coupling were investigateed. The results showed that 50%PEG400 as co-solvent, the catalytic activities of Cat was similar with in 1,4-dioxane, and the conversion of 1 was nearly 100% at 110 ℃ for 3 h at loading of 0.1 mol%, and was 57% at 0.01 mol% at 110 ℃ for 21 h(TON 5 700). It was found that the Cat can be recycled and reused once at loading of 0.1 mol%.
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Received: 07 April 2015
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2015, Vol. 23 
