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| Synthesis of Novel 1H-［1,2,3］triazolo［4,5-c］pyridazine Compounds |
| SHAO Shuai1,2, GU Wei1, LIU Jia-kuo1, NIE Ai-hua1 |
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Abstract Sixteen novel 1H-［1,2,3］triazole［4,5-c］pyridazine compounds were synthesized from aromatic amine， iodomethane， tert-butyl 4-［(methylsulfonyl)oxy］piperidine-1-carboxylate and 2-(2-bromoethoxy)tetrahydro-2H-pyran by substitution, oxidization and Suzuki reaction， using 3,4,6-trichloropyridazine and 4-iodo-1H-pyrazole as starting materials. The structures were characterized by 1H NMR and ESI-MS.
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Received: 26 November 2014
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2015, Vol. 23 
